HIV broadly neutralizing antibody targets
Progress in the last year has provided support for the use of rationally stabilized whole HIV-1
trimers as immunogens for eliciting antibodies to multiple epitopes. Furthermore, the
increasing number of broad and potent antibodies with the potential for synergistic/
complementary combinations opens up new avenues for preventing and treating HIV-1
infection.
trimers as immunogens for eliciting antibodies to multiple epitopes. Furthermore, the
increasing number of broad and potent antibodies with the potential for synergistic/
complementary combinations opens up new avenues for preventing and treating HIV-1
infection.
Summary
Progress in the last year has provided support for the use of rationally stabilized whole HIV-1 trimers as immunogens for eliciting antibodies to multiple epitopes. Furthermore, the increasing number of broad and potent antibodies with the potential for synergistic/complementary combinations opens up new avenues for preventing and treating HIV-1 infection.
Lippincott Williams & Wilkins